Early and precise cancer diagnosis substantially improves patient survival. Recent work has revealed that the levels of multiple microRNAs in serum are informative as biomarkers for the diagnosis of cancers. Researchers designed a DNA molecular computation platform for the analysis of miRNA profiles in clinical serum samples. A computational classifier is first trained in silico using miRNA profiles from The Cancer Genome Atlas. This is followed by a computationally powerful but simple molecular implementation scheme using DNA, as well as an effective in situ amplification and transformation method for miRNA enrichment in serum without perturbing the original variety and quantity
Screenshot: Warner Bros. Bad news for Max subscribers who’ve made re-watching The Lord of the Rings extended editions an annual New Year tradition: the third film in the trilogy, The Return of the King — which just celebrated its 20th anniversary! —is only available to stream in its theatrical version. No ancient evil is to blame, thankfully; it’s an unspecified “tech issue,” according to a Max spokesperson who responded to a comment request from Vulture after the issue was noted by dismayed fans on Reddit . The fact that The Return of the King extended edition is merely temporarily unavailable is actually good news given Max’s track record for removing content in the past, and the explanation makes sense considering The Fellowship of the Ring and The Two Towers remain available in both their theatrical and extended editions. The Max spokesperson assured Vulture that The Return of the King extended edition will be, ah, returning soon to the service, though as of this writing i
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